Credit HDR Architects
Project Highlights
  • 185,000 SF of flexible laboratory space
  • Designed to VC-A vibration threshold and for high performance storage
  • Distinctive exterior cladding featuring metal panel, glazing, and perforated metal panel scrim
  • Underground utility and pedestrian tunnels connect the new facility to both the existing central utility plant and adjacent Mayo facilities

The Mayo Clinic Anna-Maria and Stephen Kellen Building, originally envisioned as a four-story research building, will now stand 11 stories tall with an additional one-level basement. Encompassing 185,000 square feet in downtown Rochester, the expanded facility is triple the footprint of the original design, a response to the growing need for scientific advancements. The building will include laboratories for wet, damp, and dry occupancies to be used for research, clinical practice, and education. The lab program is VC-A vibration threshold, Risk Category-IV for highly toxic material storage, and designed for high performance and spill containment. The high-profile exterior communicates Mayo Clinic’s commitment to transformative biomedical research and furthering innovation.



cantilevered slab edge


approach accommodates 30’ grade change


of hazardous research materials
Service Provided
  • Structural engineering


Designed to support Mayo Clinic’s future expansion plans, a key challenge was integrating the new high-profile facility with an existing building. The structural system is partial post-tensioned cast-in-place concrete with a wide module forming system. A highly complex cantilevered slab edge accommodates recessed heating, curtain wall and scrim attachment and post-tensioning anchors. A repetitive forming layout assures reliable reuse of materials combined with column alignment permits the use of a flying formwork system supporting an aggressive cycle time per floor. The lateral system incorporates unbraced frames at each grid for wind and unbalanced earth pressures. The foundations are high-capacity drilled piers extending to competent bedrock. MBJ utilized a special foundation approach incorporating permanent prestressed tie backs in order to accommodate a 30’ grade change to the adjacent existing building. The structural design also took into consideration safe containment of hazardous research materials.

The distinctive exterior cladding of the facility features metal panel, glazing, and perforated metal panel scrim while a two-story entry level lobby showcases exposed concrete finishes. Performance features include variable floor loading, underground pedestrian and utility distribution tunnels, and matched floor elevations to the adjacent existing laboratory building.


Rochester, MN


Estimated 2024

Construction Cost:



Mayo Clinic


HDR Architects

MEP Consultant:

HDR Architects


Knutson Construction

Climate Consulting: